Movie 3

Acute inhibition of aPKC leads to apical constriction of eye discs and the neuroepithelium in whole mount brains. Whole mount apkcas4 mutant brain expressing Baz::GFP and Mira::mCherry (not shown) prior and after addition of 10μM 1NA-PP1. Z stacks collected every 3min, movie displayed at 7 frames per second. 0′ marks the addition of 10μM 1NA-PP1. Time hh:mm.

A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila

Matthew Hannaford, Nicolas Loyer, Francesca Tonelli, Martin Zoltner, and Jens Januschke

Development 2019. 146:None-None; doi: 10.1242/dev.170589