Movie 4

General view of the wing disc showing the delamination of apoptotic cells. Nuclei marked in green indicate DBS-S activation, LifeAct-Ruby shows actin in red. The time-lapse is showing a cross-section of a wing imaginal disc. Notice the progressive the migration of GFP positive nuclei together with actin-enriched structures towards the basal side of the wing epithelium (white arrowheads). The recording started 90 minutes after irradiation and it lasted for 40 minutes. Snapshots were acquired every 2 minutes.

Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells

Luis Alberto Baena-Lopez, Lewis Arthurton, Marcus Bischoff, Jean-Paul Vincent, Cyrille Alexandre, and Reuben McGregor

Development 2018. 145:None-None; doi: 10.1242/dev.170811