Movie 3

MMPs extend and retract long filopodia during migration. Time-lapse imaging of early MMP migration in a six1b:lyn-GFP transgenic embryo with high spatiotemporal resolution. Images were taken every 80 seconds from 30 to 37 hpf. At this resolution, long filopodia can be clearly seen extending and retracting from all MMPs. This time-lapse is representative of embryos imaged at this resolution (N=3). Scale bar is 100 μm.