β-cell-specific sFlt1 expression results in markedly reduced intra-islet vasculature. Progressive planes in a Z-stack from confocal imaging of pancreatic islets in 48 hpf Tg(ins:sflt1); Tg(fli:GFP) zebrafish, after immunostaining for Insulin (red) and GFP. Movie corresponds to Figure 2j.
Sri Teja Mullapudi, Giulia L. M. Boezio, Andrea Rossi, Michele Marass, Ryota L. Matsuoka, Hiroki Matsuda, Christian S. M. Helker, Yu Hsuan Carol Yang, and Didier Y. R. Stainier
Development
2019. 146:None-None; doi: 10.1242/dev.173674