Movie 7

Live imaging shows lack of vasculature and circulation in Tg(ins:sflt1) pancreas. Spinning disk confocal imaging of the pancreatic islet in 120 hpf Tg(ins:sflt1); Tg(gata1:DsRed); Tg(fli:GFP) zebrafish. Faint red signal in the anterior region of the pancreas (outlined in white) is from β-cells. Scale bar, 40 µm.

Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function

Sri Teja Mullapudi, Giulia L. M. Boezio, Andrea Rossi, Michele Marass, Ryota L. Matsuoka, Hiroki Matsuda, Christian S. M. Helker, Yu Hsuan Carol Yang, and Didier Y. R. Stainier

Development 2019. 146:None-None; doi: 10.1242/dev.173674

Download Original Video