Movie 6

Microglial phagocytosis is reduced in animals treated with L-SOP. Time-lapse imaging of a microglial cell in a mpeg1:GFP animal treated with L-SOP. The microglial cell approaches a PI+ cell, but does not engulf it. The movie was recorded from 30 to 72 min following injury. Scale bar, 15 μm.

Rapid clearance of cellular debris by microglia limits secondary neuronal cell death after brain injury in vivo

Chiara Herzog, Laura Pons Garcia, Marcus Keatinge, David Greenald, Christian Moritz, Francesca Peri, and Leah Herrgen

Development 2019. 146:None-None; doi: 10.1242/dev.174698