Movie 6

Myosin accumulates in proepicardial cells. In vivo time-lapse imaging of epi:GFP;myl12.1:mCherry 52-hpf embryo during 7 h. Optical section zoomed view of the proepicardial (PE) region. GFP labels dorsal pericardial (DP) cells (green). myosin12.1-mCherry is shown in red. Note the presence of myosin-positive PE cells and PE cells that are advected in the pericardial cavity. Scale bar: 50 μm. Shown is a representative movie from ≥ 3 biological and ≥ 2 technical replicates.

Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells

Laura Andrés-Delgado, Alexander Ernst, María Galardi-Castilla, David Bazaga, Marina Peralta, Juliane Münch, Juan M. González-Rosa, Inês Marques, Federico Tessadori, José Luis de la Pompa, Julien Vermot, and Nadia Mercader

Development 2019. 146:None-None; doi: 10.1242/dev.174961