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3D-reconstruction of LC3 decorated p62/SQSTM1 bodies
LC3 decorated p62/SQSTM1 bodies identified in epithelial cells of Ho_CS polyps macerated after 35 days at 10°C. Image acquired on a Leica SP8 confocal microscope, 3D reconstruction performed with Bitplane Imaris.

Deficient autophagy in epithelial stem cells drives aging in the freshwater cnidarian Hydra

Szymon Tomczyk, Nenad Suknovic, Quentin Schenkelaars, Yvan Wenger, Kazadi Ekundayo, Wanda Buzgariu, Christoph Bauer, Kathleen Fischer, Steven Austad, and Brigitte Galliot

Development 2020. 147:None-None; doi: 10.1242/dev.177840