Movie 1

Three-dimensional visualization of the 5348 retinal cells from the 10X datasets embedded in a 3D UMAP to show the extent of the 14 clusters transcriptional relationships in a well-defined continuum.
The distribution of the 14 clusters of E15.5 mouse retina can be better distinguished in three-dimensional space. This movie is a dynamic visualization of the 3D UMAP (Uniform Manifold Approximation and Projection) that illustrates the topological structure of 5348 single-cell transcriptomes, showing the relative position of the clusters. It emphasizes the connection between the progenitors (green) which are connected to the differentiated cell types through the neuroblast group (blue). These cell types are organized in three distinct groups: the photoreceptors (purple), the AC/HC (grey/black) and the RGCs (orange).