Movie 6

Simulation of rotation of a long (1.5 axial ratio) spindle with flattened poles and long astral microtubules. This spindle has the axial ratio of the shortest mei-2(ct98) spindles that rotate partially to a diagonal angle relative to the cortex but with poles shaped like those of a control spindle. This shape is also similar to that of knl-1,3(kd) spindles that partially rotate or fail to rotate. Astral microtubules are long due to a polymerization rate of 0.18 μm/s.

Spherical spindle shape promotes perpendicular cortical orientation by preventing isometric cortical pulling on both spindle poles during C. elegans female meiosis

Elizabeth Vargas, Karen P. McNally, Daniel B. Cortes, Michelle T. Panzica, Brennan M. Danlasky, Qianyan Li, Amy Shaub Maddox, and Francis J. McNally

Development 2019. 146:None-None; doi: 10.1242/dev.178863