Movie 2

Live-imaging of RNAP2 Ser2ph and miR-430 transcripts in the 1k- to 2k-cell stage embryo.
The embryo injected with RNAP2 Ser2ph-Fab (Alexa488) and miR-430 Morpholino probe (Cy3) was imaged every minutes using a light sheet microscope (SiMView). The maximum intensity projections of 30 z-sections with 2 μm intervals with merged images are shown.

Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis

Yuko Sato, Lennart Hilbert, Haruka Oda, Yinan Wan, John M. Heddleston, Teng-Leong Chew, Vasily Zaburdaev, Philipp Keller, Timothee Lionnet, Nadine Vastenhouw, and Hiroshi Kimura

Development 2019. 146:None-None; doi: 10.1242/dev.179127