Movie 16

Live light sheet time lapse movie of Irx3/5-/-;H2B-GFP anterior hindlimb mesoderm at 29 som. stage showed failed cell division following condensation of chromatin at metaphase and subsequent evidence of chromatin fragmentation. Time course is 80 min..

IRX3/5 regulate mitotic chromatid segregation and limb bud shape

Hirotaka Tao, Jean-Philippe Lambert, Theodora M. Yung, Min Zhu, Noah A. Hahn, Danyi Li, Kimberly Lau, Kendra Sturgeon, Vijitha Puviindran, Xiaoyun Zhang, Wuming Gong, Xiao Xiao Chen, Gregory Anderson, Daniel J. Garry, R. Mark Henkelman, Yu Sun, Angelo Iulianella, Yasuhiko Kawakami, Anne-Claude Gingras, Chi-chung Hui, and Sevan Hopyan

Development 2020. 147:None-None; doi: 10.1242/dev.180042