Movie 2

Optical projection tomography demonstrated the smaller and mishapen limb bud of Irx3/5^-/-;Esr1-Cre;Confetti embryos at 37 som. Anterior is upward, dorsal view shown at first frame.

IRX3/5 regulate mitotic chromatid segregation and limb bud shape

Hirotaka Tao, Jean-Philippe Lambert, Theodora M. Yung, Min Zhu, Noah A. Hahn, Danyi Li, Kimberly Lau, Kendra Sturgeon, Vijitha Puviindran, Xiaoyun Zhang, Wuming Gong, Xiao Xiao Chen, Gregory Anderson, Daniel J. Garry, R. Mark Henkelman, Yu Sun, Angelo Iulianella, Yasuhiko Kawakami, Anne-Claude Gingras, Chi-chung Hui, and Sevan Hopyan

Development 2020. 147:None-None; doi: 10.1242/dev.180042

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