Movie 5

Live imaging of migrating MGE cortical interneurons in a 3D Matrigel assay under control conditions. Medial ganglionic eminence (MGE) explant left, outgrowth area right. Interneurons migrating away from E14.5 Dlx5/6-CIE MGE explants were imaged for 12 hours in control conditions. Representative tracks from 5 cells demonstrate interneurons migrating in consistent, straight trajectories.

JNK signaling is required for proper tangential migration and laminar allocation of cortical interneurons

Abigail K. Myers, Jessica G. Cunningham, Skye E. Smith, John P. Snow, Catherine A. Smoot, and Eric S. Tucker

Development 2020. 147:None-None; doi: 10.1242/dev.180646