Movie 1
Related to Figure 1. Neural crest migration during optic cup morphogenesis. 12.5-24.5 hpf timelapse of a Tg(β-actin2:EGFP-CAAX);Tg(sox10:memRFP) double transgenic embryo. EGFP-CAAX labels all cell membranes (green), while membrane-bound RFP (magenta) labels only the neural crest. Dorsal view, single confocal section through the dorsal/ventral midpoint of the optic cup. Nasal (anterior) is to the right, temporal (posterior) to the left. ΔT between z-stacks, 3 minutes 30 seconds.
Optic cup morphogenesis requires neural crest-mediated basement membrane assembly
Development 2020. 147:None-None; doi: 10.1242/dev.181420