Movie 1

A Light Sheet time-lapse movie following the dynamics of endogenously expressed Dorsal-GFP in the entire embryo. The nuclear Dorsal gradient, which can be seen in nuclei at the ventral side (bottom) already at NC 12, is lost during nuclear divisions and is re-generated at the onset of each nuclear cycle.

Dynamics of Spaetzle morphogen shuttling in the Drosophila embryo shapes gastrulation patterning

Neta Rahimi, Inna Averbukh, Shari Carmon, Eyal D. Schejter, Naama Barkai, and Ben-Zion Shilo

Development 2019. 146:None-None; doi: 10.1242/dev.181487