Movie 3

Triacsin C treatment impairs preimplantation embryonic development.
Preimplantation development of embryos developed from non-delipidated (Delipidation-) or delipidated (Delipidation+) MII oocytes subjected to IVF and cultured in the presence or absence of Triacsin C. Treatment of embryos with DMSO was used as a control. Images were acquired every 15 min. Time indicates hours, minutes, and seconds from 6 h after IVF (mp4; 4.4 MB).

Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development

Ryutaro Aizawa, Megumi Ibayashi, Takayuki Tatsumi, Atsushi Yamamoto, Toshiaki Kokubo, Naoyuki Miyasaka, Ken Sato, Shuntaro Ikeda, Naojiro Minami, and Satoshi Tsukamoto

Development 2019. 146:None-None; doi: 10.1242/dev.181925