Movie 2

Ciliary motility is inhibited by 2% methylcellulose. Realtime movie of ciliary motility in control and methylcellulose treated embryo. A, B or C in the movie showed ciliary motility in epithelial ectoderm, neural ectoderm or gastrocoel roof plate, respectively. D in the movie showed neurula rotation. Motility of cilia on the epithelial ectodermal cells, neural ectodermal cells or gastrocoel roof plate cells was effectively inhibited by methylcellulose. Furthermore, neurula rotation was completely inhibited by methylcellulose.

Cilia-driven asymmetric Hedgehog signalling determines the amphioxus left-right axis by controlling Dand5 expression

Xin Zhu, Chenggang Shi, Yanhong Zhong, Xian Liu, Qiuning Yan, Xiaotong Wu, Yiquan Wang, and Guang Li

Development 2020. 147:None-None; doi: 10.1242/dev.182469