Movie 8

Live imaging for separase sensor in the stable cyclin B2 expressed GDF9-Ccnb1−/− oocytes. The GDF9-Ccnb1−/− oocytes expressing separase sensor and Myc-Δ50cyclin B2 with time shown (h:min:s) relative to GVBD. Bar, 20 μm.

The cyclin B2/CDK1 complex inhibits separase activity in mouse oocyte meiosis I

Jian Li, Ying-Chun Ouyang, Chun-Hui Zhang, Wei-Ping Qian, and Qing-Yuan Sun

Development 2019. 146:None-None; doi: 10.1242/dev.182519