Movie 4

Cranial neural crest cell directionality is altered after AQP-1 manipulation. Premigratory neural crest were transfected with pMES (control) or AQP-1 FL and neural tubes were plated in the presence of branchial arch 2 (ba2) tissue as a source of known endogenous chemoattraction. Images were collected every 5 minutes and a total of approximately 18 hours of elapsed time is shown. Scale bar= 50 um.