Movie 1

Migration of Co MO-injected NC cells. NC explants of embryos that were injected with 8 ng Co MO and 500 pg GAP43-GFP and 400 pg H2B-mcherry RNA to mark the membrane (green) and the nucleus (red). The cells were observed using spinning disc microscopy (40x objective). Z-stacks of 5-7 slices were taken every 90 seconds for a time period of 20 minutes. The cells exhibited intense protrusive activity.