Movie 1

3D projection of a section of the fissure margins immediately anterior to the anterior point of closure of a CS17 human eye. Blue: DAPI, Green: Phalloidin, Magenta: WGA (Wheat Germ Agglutinin, labelling cell membranes). Cells at the fissure margins have a rounded morphology.

A molecular and cellular analysis of human embryonic optic fissure closure related to the eye malformation coloboma

Aara Patel, Glenn Anderson, Gabriel L. Galea, Monika Balys, and Jane C. Sowden

Development 2020. 147:None-None; doi: 10.1242/dev.193649