Movie 4

3D projection of a section of the fissure margins at the posterior point of closure of a CS17 human eye. Blue: DAPI, Green: Phalloidin, Red: PAX6, Magenta: WGA (Wheat Germ Agglutinin, labelling cell membranes). Puncta of strong phalloidin staining are visible in cells at the point of closure.

A molecular and cellular analysis of human embryonic optic fissure closure related to the eye malformation coloboma

Aara Patel, Glenn Anderson, Gabriel L. Galea, Monika Balys, and Jane C. Sowden

Development 2020. 147:None-None; doi: 10.1242/dev.193649