Movie 4
3D projection of a section of the fissure margins at the posterior point of closure of a CS17 human eye. Blue: DAPI, Green: Phalloidin, Red: PAX6, Magenta: WGA (Wheat Germ Agglutinin, labelling cell membranes). Puncta of strong phalloidin staining are visible in cells at the point of closure.
A molecular and cellular analysis of human embryonic optic fissure closure related to the eye malformation coloboma
Development 2020. 147:None-None; doi: 10.1242/dev.193649