Movie 2.

MCC-deficient embryos struggle to divide. A bovine zygote following BUB1B MAO microinjection attempted to divide by forming multiple cleavage furrows, but never successfully completed cytokinesis.

Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development

Kelsey E. Brooks, Brittany L. Daughtry, Brett Davis, Melissa Y. Yan, Suzanne S. Fei, Selma Shepherd, Lucia Carbone, and Shawn L. Chavez

Development 2022. 149:None-None; doi: 10.1242/dev.198341