Movie 3.

Multipolar divisions are observed in MCC-deficient embryos. Certain bovine zygotes were able to undergo cytokinesis even with BUB1B knockdown, but these divisions were abnormal with multipolar cleavage.

Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development

Kelsey E. Brooks, Brittany L. Daughtry, Brett Davis, Melissa Y. Yan, Suzanne S. Fei, Selma Shepherd, Lucia Carbone, and Shawn L. Chavez

Development 2022. 149:None-None; doi: 10.1242/dev.198341