To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 3. Multipolar divisions are observed in MCC-deficient embryos. Certain bovine zygotes were able to undergo cytokinesis even with BUB1B knockdown, but these divisions were abnormal with multipolar cleavage. Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development Kelsey E. Brooks, Brittany L. Daughtry, Brett Davis, Melissa Y. Yan, Suzanne S. Fei, Selma Shepherd, Lucia Carbone, and Shawn L. Chavez Development 2022. 149:None-None; doi: 10.1242/dev.198341 Download Original Video