To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 4. MCC deficiency causes blastomere asymmetry. Besides abnormal divisions, BUB1B-injected bovine embryos often exhibited blastomere asymmetry following the multipolar cleavage. Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development Kelsey E. Brooks, Brittany L. Daughtry, Brett Davis, Melissa Y. Yan, Suzanne S. Fei, Selma Shepherd, Lucia Carbone, and Shawn L. Chavez Development 2022. 149:None-None; doi: 10.1242/dev.198341 Download Original Video