Movie 4.
MCC deficiency causes blastomere asymmetry. Besides abnormal divisions, BUB1B-injected bovine embryos often exhibited blastomere asymmetry following the multipolar cleavage.
Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development
Development 2022. 149:None-None; doi: 10.1242/dev.198341