Movie 3

WT1(-) E12.5 embryo imaged in situ via micro-CT with Amira segmentation of key volumes. This rendering is also shown in Figure 7C. Note the lack of dorsal volume creating a confined growth environment. The total cavity volume in this embryo is almost double that of the WT1(-) embryo shown in Figure 7B and Movie 2, yet the dorsal volume is equal indicating increased secretion and dorsal-ventral cavity volume redistribution.