Movie 1.

The control molar epithelium becomes narrower and deeper as it invaginates into underlying mesenchyme. Time-lapse imaging of frontal tissue section of E11.5 control mandible (Fgf8CreER;R26mT/mG) for 16 hours. Green (mG-positive): dental epithelial cells; red (mT-positive): non-dental epithelial cells.

Early perturbation of Wnt signaling reveals patterning and invagination-evagination control points in molar tooth development

Rebecca Kim, Tingsheng Yu, Jingjing Li, Jan Prochazka, Amnon Sharir, Jeremy B. A. Green, and Ophir D. Klein

Development 2021. 148:None-None; doi: 10.1242/dev.199685