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Movie 1

KTR sensor reveals dynamic ERK activity in ESCs growing in serum + LIF. Time-lapse imaging of ERKKTR expressing cells growing in serum + LIF with (left) and without MEKi (right). Frame rate is 20 s, total duration is 101 min. Scale bar: 20 μm.

Intermittent ERK oscillations downstream of FGF in mouse embryonic stem cells

Dhruv Raina, Fiorella Fabris, Luis G. Morelli, and Christian Schröter

Development 2022. 149:None-None; doi: 10.1242/dev.199710