Movie 12.

Patronin regulates microtubule organization and dynamics. Microtubule dynamics visualized in the amnioserosa in wildtype embryos and in PatroninEY05252 embryos in a Jupiter GFP background. (A) Zoomed out view depicting multiple cells. (B) Zoomed in view containing one cell with multiple pulsed constriction cycles showing microtubule reorganisation and aster/cage formation (red arrowheads in control) and anchoring (yellow arrowheads in PatroninEY05252). Scale bar -5 μm. (Related to Fig 6)

The microtubule end-binding proteins EB1 and Patronin modulate the spatiotemporal dynamics of myosin and pattern pulsed apical constriction

Anwesha Guru, Surat Saravanan, Deepanshu Sharma, and Maithreyi Narasimha

Development 2022. 149:None-None; doi: 10.1242/dev.199759