Movie 2.

Video of live cell imaging of SIR-DNA dye recording the first mitotic division in Smc3Δ/Δ cKO zygotes. Related to Fig. 4C-E. Left panel shows the SIR-DNA channel and the right panel shows the merged stack of the SIR-DNA channel (magenta) and the widefield channel (cyan). The magenta arrow indicates the micronucleus formed from lagging chromosomes. Scale bar, 10 μm.

Maternal Smc3 protects the integrity of the zygotic genome through DNA replication and mitosis

Wei-Ting Yueh, Vijay Pratap Singh, and Jennifer L. Gerton

Development 2021. 148:None-None; doi: 10.1242/dev.199800