Movie 11.

Collective organization and migration is disrupted upon loss of NMIIA. Confocal live imaging of GFP expressing cells in E15.5 Myh9^lox/lox; R26^mTmG/+; Crect^Tg/0 secondary palate sagittal section shows failure to form collective epithelial trails and islands and a lack of directional MES cell movement. Images were captured every 15 minutes for 20 hours. Scale bar, 15μm.

A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis

Teng Teng, Camilla S. Teng, Vesa Kaartinen, and Jeffrey O. Bush

Development 2022. 149:None-None; doi: 10.1242/dev.200181

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