Loss of apoptosis does not disrupt MES breakage. Confocal live imaging of GFP expression in E14.75 Baxlox/lox; Bak-/-; R26mTmG/+; CrectTg/0 secondary palate sagittal section shows the breakage of MES. Green asterisk indicates a separation of MES cells that continues to grow; magenta asterisk indicates a separation of MES cells that reduces and is eventually eliminated. Images were captured every 15 minutes for 20 hours. Scale bar, 15μm.