Movie 7.

Loss of apoptosis does not disrupt MES breakage. Confocal live imaging of GFP expression in E14.75 Bax^lox/lox; Bak^-/-; R26^mTmG/+; Crect^Tg/0 secondary palate sagittal section shows the breakage of MES. Green asterisk indicates a separation of MES cells that continues to grow; magenta asterisk indicates a separation of MES cells that reduces and is eventually eliminated. Images were captured every 15 minutes for 20 hours. Scale bar, 15μm.

A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis

Teng Teng, Camilla S. Teng, Vesa Kaartinen, and Jeffrey O. Bush

Development 2022. 149:None-None; doi: 10.1242/dev.200181

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