Movie 2.
McSCs in a regenerating embryo following ALDH2 inhibitor (CVT-10216) treatment. Movie showing 3D rendering of a representative McSC cluster during regeneration. Here, an embryo expressing transgenes crestin:mCherry and mitfa:GFP embryo is imaged at the onset of regeneration during CVT-10216 treatment and following MoTP treatment. In this example, two cells express mCherry, but while GFP is detected in a neighbouring cell, it is not expressed in this McSC niche. See Fig. S2, CVT-10216 example 2.
Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells
Development 2022. 149:None-None; doi: 10.1242/dev.200277