Movie 4.

Aldh2i inhibits McSCs ability to generate progeny Time-lapse video of a Tg(crestin:mCherry;mitfa:GFP) embryo during McSC regeneration in the presence of ALDH2i. Embryos were treated with CVT-10216 to inhibit Aldh2, and co-treated with MoTP to kill differentiated melanocytes, and initiate melanocyte regeneration. McSCs were followed for over 14 hours (post MoTP washout, but in the presence of ALDH2i).