Movie 1.
Time-lapse lineage tracing of EHT in control embryos. The fate transition via EHT was observed in control Tg(kdrl:mCherry/cmyb:EGFP) embryo from 34 hpf to 40 hpf by Andor Dragonfly 505 confocal microscope. The white arrows indicate the HEC and emerging HSPCs.
DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling
Development 2022. 149:None-None; doi: 10.1242/dev.200390