To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 2. Time-lapse lineage tracing of EHT in dnmt1 atgMO-injected embryos. The fate transition via EHT was impaired in dnmt1 morphant Tg(kdrl:mCherry/cmyb:EGFP) embryo from 34 hpf to 40 hpf. The white arrow indicates the HEC and emerging HSPC. DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling Yan Li, Chao Tang, Fan Liu, Caiying Zhu, Feng Liu, Ping Zhu, and Lu Wang Development 2022. 149:None-None; doi: 10.1242/dev.200390 Download Original Video