Movie 2.

The T-reverse type arrangement observed in the 4-cell stage of the C. elegans embryo. The hmr-1 and hmp-2-double-knockdown embryos with a lon-1(e185) mutant background. The embryo is identical to that shown in Fig. 1A(a-4) and Fig. 3A of this paper and Fig. 7C of Yamamoto and Kimura (2017).

The extra-embryonic space and the local contour are crucial geometric constraints regulating cell arrangement

Sungrim Seirin-Lee, Kazunori Yamamoto, and Akatsuki Kimura

Development 2022. 149:None-None; doi: 10.1242/dev.200401