Movie 4.
Knockdown of Dlg1 affects apical myosin contractions in the flanking cells. Ventral surface view of a control embryo and a dlg1 RNAi embryo expressing E-cadherin-GFP (magenta) and Sqh-mCherry (green) during late apical constriction. For each movie, two representative flanking cells are highlighted in magenta. T = 0:00 (mm:ss) corresponds to the onset of gastrulation.
The cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination
Development 2022. 149:None-None; doi: 10.1242/dev.200468