Movie 1.

Mice survival has an improvement after SAM supplementation. At the fourth day of Tmx induction, the Mat2aiIEC-KO +SAM mice (Three lively mice on the right) were still active and then lived one or two more days compared to the Mat2aiIEC-KO +Vehicle mice (Two dying mice on the left) which were poor in health and died soon.

S-adenosyl-L-methionine supplementation alleviates damaged intestinal epithelium and inflammatory infiltration caused by Mat2a deficiency

Miao-Lin Li, Si-Yi Cao, Jia Qu, Lei Zhang, Qiang Gao, Xu Wang, Miao Yin, Ying Liu, Ming-Zhu Lei, and Qun-Ying Lei

Development 2023. 150:None-None; doi: 10.1242/dev.201135