Movie 4.
SAC-impaired P. mammillata 256-cell stage embryos undergoing mitosis with and without spindle microtubules. Video microscopy of representative 256-cell stage embryos injected with RNA encoding Mad2-DN and treated with either DMSO (left) or nocodazole (right). Images were acquired every two minutes. Nuclei were visualized by NLS-3xVenus.
Acquisition of the spindle assembly checkpoint and its modulation by cell fate and cell size in a chordate embryo
Development 2023. 150:None-None; doi: 10.1242/dev.201145