Movie 1.
Development of chimaeric embryo from the 8-cell stage to the blastocyst stage. β-tubulin-GFP allows for labelling microtubules of the mitotic spindle (green) and histone H2B-mCherry allows the labelling of cell nuclei (red). CAG::H2B-GFP ESCs are visible in green.
Multi-level Fgf4- and apoptosis-dependent regulatory mechanism ensures the plasticity of ESC-chimaeric mouse embryo
Development 2023. 150:None-None; doi: 10.1242/dev.201756