Movie 4.
Apoptosis of the ICM cell in the chimaeric embryo at the early blastocyst stage. ESCs are not visible to better show the blastomere undergoing elimination. The nucleus of the blastomere undergoing elimination is marked with a white circle.
Multi-level Fgf4- and apoptosis-dependent regulatory mechanism ensures the plasticity of ESC-chimaeric mouse embryo
Development 2023. 150:None-None; doi: 10.1242/dev.201756