Movie 1.
Release of NICD from OptIC-Notch. OptIC-Notch is activated with 458 nm light for 10 minutes. Release of NICD and its accumulation in the nucleus over time is shown by simultaneous imaging of the mCherry tag. Scale bar = 20 μm.
OptIC-Notch reveals mechanism that regulates receptor interactions with CSL
Development 2023. 150:None-None; doi: 10.1242/dev.201785