Movie 2.
Release of NICD from OptIC-Notch{ω}. OptIC-Notch{ω} is activated with 458 nm light for 20 minutes. Release of NICD and its accumulation in the nucleus over time is shown by simultaneous imaging of the mCherry tag. Scale bar = 20 μm.
OptIC-Notch reveals mechanism that regulates receptor interactions with CSL
Development 2023. 150:None-None; doi: 10.1242/dev.201785