Movie 4.
Smad6 mutant embryonic liver lacks organized αSMA staining and large vessels. XY optical sections of light-sheet microscopy on whole E16.5 Smad6iΔ/iΔ liver stained for Lyve-1 (magenta) and αSMA (cyan). Scale bar, 1000μm.
Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development
Development 2023. 150:None-None; doi: 10.1242/dev.201811