Movie 6.
Timelapse confocal imaging of the developing caudal venous plexus of a laterally mounted rasa1-/- Tg(kdrl:mCherry) embryo from 24-30 hpf. Imaging was performed with 15 min intervals and shown at 2 fps. Note the cavernous AVM at the posterior of the tail, partially filled with stagnant blood.
rasa1-related arteriovenous malformation is driven by aberrant venous signalling
Development 2023. 150:None-None; doi: 10.1242/dev.201820