Movie 3.
Representative SOX2-GFP iPSC Aggregates Undergoing Inner Ear Organoid Induction. A 24-hour time-lapse recording of three organoids between days 8-9. Z-stacked images were taken every hour. Note the thicken SOX2-GFP-positive patches reminiscent of placodes dotting the surface epithelium.
Mapping oto-pharyngeal development in a human inner ear organoid model
Development 2023. 150:None-None; doi: 10.1242/dev.201871