Movie 1.
Time-lapse lineage tracing of EHT in control embryos. The fate transition via EHT was observed in control Tg(kdrl:mCherry/runx1:en-GFP) embryo from 36 hpf to 41 hpf by Andor Dragonfly 505 confocal microscope. The white arrows indicate the HEC and emerging HSPCs.
The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling
Development 2023. 150:None-None; doi: 10.1242/dev.201890