Movie 2.
Time-lapse lineage tracing of EHT in csde1 mutants. The fate transition via EHT was impaired in csde1 knockout Tg(kdrl:mCherry/runx1:en-GFP) embryo from 36 hpf to 41 hpf. The white arrow indicates the HEC and emerging HSPC.
The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling
Development 2023. 150:None-None; doi: 10.1242/dev.201890